An Australian study into amino acid depletion and sub-health has found promising results with a complex amino acid supplement.

Sub-health is an intermediate state between health and disease. Sub-health can be a chronic condition, usually indicated by low energy, loss of vitality, altered sleeping patterns, and increased incidence of viral infections. Sub-health can also lead to the debilitating medical conditions of chronic fatigue syndrome and fibromyalgia.

Many illnesses can result in amino acid depletion. Amino acid imbalance is often found in cancer-related fatigue, for example. Could amino acid imbalance also result from sub-health? If so, would correcting this imbalance improve health?

Some amino acids are synthesized in the body, but the essential amino acids are obtained through food.

If people are unable to ingest the correct quantities of essential amino acids in their diet, they are often given amino acid supplements to correct the imbalance. However, these supplements contain a complex formula of ingredients. In addition to perfecting the formula, developers must ensure the taste is palatable.

Amino acid supplement study

Researchers (R Dunstan, S Sparkes, et al) with the School of Environmental and Life Sciences, University of Newcastle, Australia, developed a study into the new, broad-spectrum amino acid dietary supplement, Fatigue Reviva (developed by TOP Nutrition Pty Ltd).

17 men reporting symptoms of sub-health took part in the 30 day trial. After the trial, 65% of the study group reported that their energy levels had significantly improved.

Urinary amino acid analysis revealed that the supplement increased the levels of valine, isoleucine and glutamic acid, and reduced levels of glutamine and ornithine.

However, some participants reported gastrointestinal symptoms. The researchers believed these symptoms were caused by the prebiotic fructooligosaccharide, an ingredient in the supplement. Further product development is needed for those patients susceptible to fructooligosaccharide.

The study concluded that this amino acid supplement could prevent fatigue, and increase wellbeing, for patients with symptoms of sub-health.

Sources:

http://www.ncbi.nlm.nih.gov/pubmed/23927677