Tag Archives: men

Arginine for Inflammation and Erectile Dysfunction

For men, arginine may pose as almost a miracle amino acid for inflammation and erectile dysfunction, but one should be wary that arginine combined with other amino acids, protein, and lifestyle changes are more likely the answer.

Arginine, has been getting a lot of attention for it can be an amazing anti-aging amino acid. It also may be useful for graying hair, loss of hair, heart disease, preventing heart failure, and possibly inflammation.

This is where pieces of the arginine amino acid puzzle starts to thicken.  Inflammation and erectile dysfunction are two problems often linked together as exemplified by the article “Reduction of Inflammation Improves Endothelial Function and ED” whereby “minimizing infection and inflammation throughout the body, including avoiding fat accumulation, should improve both vascular and erectile health.”

The link may be attributed to arginine being needed by the body to make nitric oxide.

Because nitric oxide is crucial for maintaining healthy blood pressure, it also helps prevent atherosclerosis, and plays a role in modulating immune system function. In addition, nitric oxide regulates several processes in the body, including fat and glucose metabolism.

Researchers found that inhibiting nitric oxide production was associated with fat gain while stimulating nitric oxide secretion was correlated with enhanced lipolysis, or fat breakdown, according to research published in the September 2006 issue of the Journal of Nutritional Biochemistry.

The best part about nitric oxide is that it is readily available on a sunny day.

Is Nitric Oxide the Cure for Inflammation and ED?

There is some strong evidence that indicates nitric oxide may help both inflammation and ED. In the study, “Role of Nitric Oxide in Inflammatory Diseases” they concluded NO (nitric oxide) inhibitors “represent important therapeutic advance in the management of inflammatory diseases”.

Additionally, the amino acid L-arginine stimulates nitric oxide, which releases “growth hormone, insulin, and other substances in the body.” Prescription drugs also may contribute to maintain the nitric oxide in the body, which can also help prevent erectile dysfunction.

In conclusion, when it comes to adults, and particularly men of industrialized countries, the issue may not be so much about consuming enough protein and amino acids, the concern might be to see the bigger picture and rooting out the problem of inflammation and erectile dysfunction, instead of just ‘curing’ this challenge with a quick fix. Certainly stress is one factor, lack of sleep another, but also being mindful of our diets and exercise.

References:

http://www.medscape.com/viewarticle/761122_18

http://articles.mercola.com/sites/articles/archive/2013/07/15/sun-exposure.aspx

http://www.livestrong.com/article/233939-l-arginine-weight-loss/

http://www.ncbi.nlm.nih.gov/pubmed/18236016

http://www.webmd.com/vitamins-supplements/ingredientmono-875-L-ARGININE.aspx?activeIngredientId=875&activeIngredientName=L-ARGININE

Part 1: Amino Acids for Men – Virility and Libido (Arginine)

The amino acids for men are the same ones that can be taken for women; however, there are specific aminos that help stimulate biological processes and boost sexual performance and virility. Erectile dysfunction (ED) is a common issue for middle-aged to older men or men with prostate problems. The consequences include a drop in self-confidence, and reduced virility, fear, anxiety, potency, and sometimes close relationships, which can lead to depression. Amino acids for men and these issues, however, may help offset some of these symptoms.

Sexual performance can have a positive effect on men’s sexual health. Specifically, the amino acids for men include arginine and ornithine. I will cover arginine here in part 1, and ornithine in part 2 of this article.

Amino acids for men – arginine

Arginine is a precursor for NO (nitric oxide), which has health benefits for the body. By increasing arginine in the body, nitric oxide will increase as well, which dilates the blood vessels and helps with blood circulation. Blood circulation is what also affects the penis.

Truly this is one of the best amino acids for men available because the nitric oxide already improves arterial elasticity, which can help reduce blood pressure as well as improve erectile processes as well. Nutrients and oxygen can also be transported more efficiently to the organs. All of this together can have a positive effect on sexual performance, endurance, and potency.

Arginine is one of those amazing amino acids for men that have no side effects. Plus it is less expensive than synthetic pills. Of course, it is does not work immediately as virility takes a few days to show up; however, the harmless qualities of arginine makes it a viable alternative or supplement.

Erectile dysfunction (ED) has been studied, says Amino Acid Studies, by pharmacologists like Professor Dirk Stichtenoth at the Institute for Clinical Pharmacology whom said, “Initial evaluations indicate positive effects” for arginine and ED. In their study at Cologne University in 1999, 26 patients with potency issues were prescribed arginine (1500mg/day). In only seven weeks a significant improvement was experienced by 73% of the participants in their erectile function.

A similar study was done in Tel Aviv University around the same time with 46 men who had ED with 31% increase in sexual function. Of all the amino acids for men out there, arginine is one of the most highly prized for the benefits for virility and potency, with absolutely no side effecs.

CONTINUE TO Part 2: Amino Acids for Men – Virility and Libido (Ornithine)

Reference:

http://www.aminoacid-studies.com/areas-of-use/virility-and-libido.html

Phenylalanine Hydroxylase and Memory Performance

Phenylalanine, an essential amino acid, is the precursor to amino acid tyrosine, which helps regulate dopamine, noradrenaline and adrenaline. Found naturally in breast milk, phenylalanine is said to have analgesic and antidepressant qualities. Phenylalanine hydroxylase (PAH) is the enzyme that catalyzes phenylalanine to tyrosine. Mutations in PAH can cause phenylketonuria (PKU), the inability to metabolize phenylalanine and a genetic disorder that can lead to intellectual disability, seizures, motor disorder and skin rashes when not monitored. Because of this association of genetic variations to cognitive ability, researchers at the National Center of Neurology and Psychiatry in Japan set out to test the effect of variations, or single nucleotide polymorphisms, of PAH on memory performance in humans.

For the experiment, researchers Toshiya Teraishi et al. used 599 healthy participants. All participants underwent interviews to make sure they had no history with psychological disorders. They were then given the Wechsler Memory Scale-Revised to evaluate memory performance in five parts: verbal memory, visual memory, general memory, attention and delayed recall. Blood samples were also taken to determine the genomic DNA of the participants and tag six different single nucleotide polymorphisms (SNP) of PAH.

The effect of variations of PAH on memory

After analyzing the test scores and associated SNPs of phenylalanine hydroxylase of the participants, researchers Teraishi et al. found a significant association of the verbal memory set of the score with five SNPs. This suggests that common variations in PAH, specifically variations with SNP marker rs2037639 and haplotype markers rs2037639 and rs10860936, can have an effect on verbal memory performance.

Because SNP rs2037639 was found in previous studies to be associated with schizophrenia in sample of Bulgarian men, the researchers believe that the particular SNP variation increases an individual’s susceptibility to the mental disorder by affecting memory performance.

They report that verbal memory is one of the most altered neurocognitive function for schizophrenics.

Source:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733818/

Does L-tryptophan Affect Women More Than Men?

An interesting study from Europe has found that depletion of the amino acid L-tryptophan affects emotional processing, specifically how we recognize fear. But are women affected more than men?

L-tryptophan is an essential amino acid, which means we must obtain it from our diet, or in supplements. L-tryptophan found in many animal and plant proteins. It has numerous functions, and has been the subject of several clinical studies for its role as producing the crucial neurotransmitter serotonin.

Serotonin is primarily found in the central nervous system, where it performs important functions. Serotonin affects memory, learning, and emotional response.

Serotonin levels are directly related to L-tryptophan intake. This means lack of L-tryptophan results in low serotonin levels, which could lead to insomnia, anxiety, and depression. Low levels of serotonin also affect mood.

L-tryptophan depletion: fear recognition different in men and women

Researchers (C Harmer, R Rogers, et al) from the University Department of Psychiatry, Warneford Hospital, Oxford, UK, selected healthy male and female volunteers to examine their responses to emotional expression, particularly fear, if their serotonin levels were low.

In this double-blind trial, the volunteers were randomly given either an amino acid drink specifically lacking in L-tryptophan, or a control drink containing a balanced mixture of amino acids. The acute L-tryptophan depletion reduced their serotonin functions.

The volunteers were given a facial expression recognition test five hours after the drink was administered. Six basic emotions were used: fear, anger, disgust, surprise, sadness, and happiness.

Results were interesting, with a distinct difference between male and female response for fear recognition only.

L-tryptophan depletion significantly impaired the women’s ability to recognize fear as a facial expression. The male volunteers were not affected, and recognized fear even if their serotonin levels were low.

Recognition of all the other basic emotions was comparable in the two groups.

The researchers concluded that acute L-tryptophan depletion does affect emotional response, and that this effect is greater in women, compared to men.

Sources:

http://www.ncbi.nlm.nih.gov/pubmed/12677354

Amino Acids Lysine, Proline, Arginine To Treat Prostate Cancer

A study into the anti-tumor effects of specific nutrients has led to positive results. A unique amino acids-plus formulation of lysine, proline, arginine, ascorbic acid, and epigallocatechin gallate was proved to have anticancer properties, and could become a natural anticancer agent to treat prostate cancer. 

Prostate cancer is the most common cancer among men, after skin cancer. In fact, about 1 man in 6 will be diagnosed with prostate cancer (U.S. data). But prostate cancer can often be treated successfully, especially if detected early.

Prostate cancer can often be found by testing for a prostate-specific antigen in the blood. A digital rectal exam is also a common screening technique. Once diagnosed and staged, prostate cancer can be treated with surgery, radiation therapy, cryotherapy, chemotherapy, hormone therapy, and other treatments.

Because some treatments, like chemotherapy, have severe side effects, scientists worldwide are studying new, non-toxic anti-cancer therapies, including some amino acids.

Amino acids nutrient study results: proliferation of prostate cancer cells reduced

Researchers Roomi MW, Ivanov V, et al, from the Matthias Rath Research, Cancer Division, Santa Clara, USA, developed a unique formula containing specific amino acids to treat prostate cancer cell lines.

Various concentrations of the amino acids lysine, proline, and arginine, were combined with ascorbic acid and epigallocatechin gallate. This mixture was tested on prostate cancer cell lines in vitro. The proliferation, or growth, of prostate cancer cells was measured.

Lysine is one of the essential amino acids, which means we must ingest it since our bodies cannot produce it by themselves. The two amino acids proline and arginine are synthesized in our bodies, though of course all amino acids can be consumed as supplements or can come from eating certain protein foods, including meats.

Results of the study were impressive. The amino acids-plus mixture produced a dose-dependent inhibition of some of the prostate cancer cell lines. The researchers concluded that the lysine, proline, and arginine amino acids, ascorbic acid, and epigallocatechin gallate mixture could become a potent anticancer agent, and could be a new treatment for prostate cancer.

Sources:

http://www.ncbi.nlm.nih.gov/pubmed/17564322