Tag Archives: lysine

Amino Acids Lysine, Proline, Arginine To Treat Prostate Cancer

A study into the anti-tumor effects of specific nutrients has led to positive results. A unique amino acids-plus formulation of lysine, proline, arginine, ascorbic acid, and epigallocatechin gallate was proved to have anticancer properties, and could become a natural anticancer agent to treat prostate cancer. 

Prostate cancer is the most common cancer among men, after skin cancer. In fact, about 1 man in 6 will be diagnosed with prostate cancer (U.S. data). But prostate cancer can often be treated successfully, especially if detected early.

Prostate cancer can often be found by testing for a prostate-specific antigen in the blood. A digital rectal exam is also a common screening technique. Once diagnosed and staged, prostate cancer can be treated with surgery, radiation therapy, cryotherapy, chemotherapy, hormone therapy, and other treatments.

Because some treatments, like chemotherapy, have severe side effects, scientists worldwide are studying new, non-toxic anti-cancer therapies, including some amino acids.

Amino acids nutrient study results: proliferation of prostate cancer cells reduced

Researchers Roomi MW, Ivanov V, et al, from the Matthias Rath Research, Cancer Division, Santa Clara, USA, developed a unique formula containing specific amino acids to treat prostate cancer cell lines.

Various concentrations of the amino acids lysine, proline, and arginine, were combined with ascorbic acid and epigallocatechin gallate. This mixture was tested on prostate cancer cell lines in vitro. The proliferation, or growth, of prostate cancer cells was measured.

Lysine is one of the essential amino acids, which means we must ingest it since our bodies cannot produce it by themselves. The two amino acids proline and arginine are synthesized in our bodies, though of course all amino acids can be consumed as supplements or can come from eating certain protein foods, including meats.

Results of the study were impressive. The amino acids-plus mixture produced a dose-dependent inhibition of some of the prostate cancer cell lines. The researchers concluded that the lysine, proline, and arginine amino acids, ascorbic acid, and epigallocatechin gallate mixture could become a potent anticancer agent, and could be a new treatment for prostate cancer.



Lysine and Stress

An interesting study concludes that foods fortified with Lysine can reduce anxiety and stress in people whose diets are Lysine-deficient. This reflects the importance of the relationship between amino acid nutrition and mental health and more specifically, Lysine and stress.

The amino acid Lysine is a vital building block for all protein in the body. Lysine plays a major role in calcium absorption; building muscle protein; recovering from surgery or sports injuries; and the body’s production of hormones, enzymes, and antibodies.

This important amino acid is found in many foods, and is easily consumed as part of a balanced diet. High protein foods such as such as eggs, meat (specifically red meat, lamb, pork, and poultry), soy, cheese (particularly Parmesan), and certain fish (such as cod and sardines) contain Lysine.

However, Lysine deficiencies can be found in communities consuming wheat as a staple food. Lysine is the limiting amino acid (the essential amino acid found in the smallest quantity in the particular foodstuff) in most cereal grains.

Lysine and stress  — reduction through fortification

As part of a three-month wheat fortification trial, dietary data were collected on five impoverished communities in northwest Syria, who depended mainly on wheat for their dietary supply of protein.

The study, reported by Nevin Scrimshaw, Miro Smriga, Shibani Ghosh, et al, from the Food and Nutrition Program, United Nations University, hypothesized that fortifying a lysine-deficient diet in poor communities would reduce anxiety and stress, and improve the quality of life. In other words, they believed that there was a genuine connection between Lysine and stress.

The study found that people on the lysine fortification diet reported significantly reduced chronic anxiety. Results indicate that not only long-term anxiety but also acute stress response is lessened by lysine fortification.

It is hoped that stress-related problems, which range from high anxiety to infectious diseases, will be solved by offering lysine fortified foods to other impoverished populations with no other source of dietary protein.


  1. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC420386/
  2. http://en.wikipedia.org/wiki/Lysine

Buy Lysine Online at:

  1. Walgreen’s
  2. GNC


Can L-lysine Help Alleviate Migraines?

Migraines are a common chronic neurological disorder characterized by moderate or severe pulsating headache attacks along with a number of autonomic nervous system symptoms. These symptoms may emerge as nausea, vomiting, sensitivity to light (photophobia), and/or increased sensitivity to sound (phonophobia). L-lysine clonixinate (lysine clonixinate) is a form of L-lysine amino acid and may be able to help with migraines.

Migraines can last anywhere from two to 72 hours and are usually treated with nonsteroidal anti-inflammatory drugs or analgesic drugs such as ibuprofen and paracetamol, and antiemetic drugs for nausea. It is estimated that 15% of the population suffer from migraines.

Researchers at the Headache Center of Rio in Brazil evaluated the efficacy and safety of an intravenous administration of L-lysine clonixinate and dipyrone for the treatment of severe headaches. L-lysine clonixinate is a form of amino acid L-lysine that is derived from nicotinic acid and serves as safe anti-inflammatory and analgesic compound. Dipyrone is a fast-acting non-opiate analgesic drug that is a common form of migraine treatment for emergency departments of Brazil.

What is L-Lysine Good for?

For the experiment researchers Abouch Krymchantowski, Henrique Carneiro, Jackeline Barbosa and Carla Jevoux recruited 30 participants from 18 to 48 years who have complaints of migraines. The subjects were split into two groups and given either L-lysine clonixinate (21 mL of 0.9% saline and 4 mL of 200 mg L-lysine clonixinate) or dipyrone (23 mL of 0.9% saline and 2 mL of 1000 mg dipyrone) for treatment of their severe migraine attack. Saline solution was used to dilute the drugs since a burning sensation at the site of injection is a common effect of L-lysine clonixinate. At half-hour intervals after administration of the injection, headache intensity, nausea, photophobia and other side effects were measured and recorded.

After evaluating the data, researchers Krymchantowski, Carneiro, Barbosa and Jevoux found at 30 minutes after injection, 0% of the dipyrone group and 13% of the L-lysine clonixinate group were free of migraine pain. At the 60-minute mark, pain free participants had increased to 13% of the dipyrone group and 73% of the L-lysine clonixinate group.

By the end of the 90-minute treatment, 33% of the dipyrone participants were pain free while almost 87% of the L-lysine clonixinate participants were free from migraine pain. Both drugs were effective in relieving nausea and photophobia by the end of treatment but more side effects, especially burning at the site of injection, was reported for the L-lysine clonixinate group.

Based on these results, the researchers conclude that L-lysine clonixinate may be a better option for treating severe migraine attacks, particularly when other drugs have shown to be ineffective for the patient.



Common Vegan Diet Deficiency… Amino Acid Lysine

People who follow a vegan diet may want to beware of a diet-based lysine amino acid deficiency which can lead to fatigue, mood swings, hair loss, unexpected weight loss, growth delays in children and anemia.

According to a 2011 Harris Interactive study, the number of people following a vegan diet in the United States has doubled since 2009 to 2.5% of the population. An amazing 7.5 million U.S. citizens now eat vegan diets that do not include any animal products – no meat, poultry, fish, dairy or eggs.

Vegan Amino Acids Deficiency

The amino acid Lysine is a common deficiency in the diet of a vegetarian, and particularly of vegans, as are amino acids in general. All 22 amino acids come from food; specifically, from proteins. While chicken and beef provide all 22 amino acids (aminos are the building blocks of proteins), animal meats are not on the vegan/vegetarian diet; however, if one is an ovo-vegetarian (one who eats eggs)j or lacto-vegetarian (one who eats dairy products) then some amino acids can be consumed for this purpose. Also, if one is a pesco-vegetarian (one who eats fish) then amino acids can be gotten that way as well. Interestingly, it is lysine that is the one amino acid that is commonly missing from most vegan menus.

High-Lysine Amino Acid Foods for Vegans and Vegetarians

Lysine is an amino acid that can come from food, but is often taken as a supplement. To obtain lysine amino acid from protein one needs 1.0 to 1.1 grams per kilogram of body weight each day (adults), especially if you are over the age of 60. High-lysine foods include legumes, quinoa, pistachios, and seitan, and need to be eaten daily. Adding enough protein to the diet is extremely important to maintain enough lysine in the body. Legumes, which include soybeans (and products from soybeans such as tofu, tempeh, soy milk, soy meats, and so on), also include beans (pinto, garbanzo, pinto and other dry beans) and their products (falafel, refried beans, and hummus), peas (black-eyed, split, green peas, etc.), lentils, and even peanuts.

There are 9 essential amino acids (EAAs) that the body cannot produce, which must be taken in through food or supplementation. The percentages of EAAs in soy products and animals are close to those in human proteins; however, non-soy plant proteins have at least one amino acid that is lower than soy proteins. Interestingly, legumes and their products are actually fairly close to the percentages in soy.

Other Foods High in the Amino Acid Lysine

Seitan and legumes, per serving, have the highest amount of the amino acid lysine. In particular, it is tempeh and tofu, soy meats, lentils, and seitan, which are highest, with other legumes and their products falling in under that. Lysine is the amino acid that is also found in decent amounts in pistachios and quinoa. As a general rule of thumb, vegans and vegetarians should try to consume the US RDA recommendations for proteins and lysine, approximately 1g/kg of protein for children, .8g/kg for people 18-59, and up to 1.3g/kg for those over age 60.

Nitrogen balance can also affect how much of the amino acid lysine one needs, as well as amino acids in general. Basically, it is simply recommended that vegans and vegetarians ensure they have more than enough protein to accommodate issues such as nitrogen imbalance. The Vegan Health organization has put together some information on nitrogen balance, as well as a chart for the protein and amino acids in foods in one of their articles on proteins and lysine for vegans.

The bottom line is that vegans and vegetarians should obtain more lysine and other amino acids through diet or supplements to ensure that their health is maintained since lysine and amino acid deficiencies are common.



Lysine and Shingles: Taking Lysine to Protect Against Shingles

Lysine for Shingles? Lysine is a commonly available amino acid found in most drugstores, but did you know that you can also use Lysine for shingles by helping relieve the agony and pain brought about by the shingles virus? 

The shingles virus is the same virus that causes chicken pox and is called the herpes zoster virus. It causes painful, fluid filled blisters and can be transmitted to people who have never had chicken pox.  Contracting the virus from someone with shingles causes the individual to contract chicken pox rather than shingles.

The elderly and people with compromised immune system are the most likely to come down with shingles. While there is a vaccine available for shingles, it is still experimental and the dose given of shingles in many times the potency of the traditional chicken pox virus that most receives as children.

Lysine Dosage for Shingles

Lysine works to fight shingles as it replaces other factors that encourage the growth of shingles blisters and usurps their role in the body. It is recommended to take a supplement of lysine if you are susceptible to the shingles virus.

If you are between shingles outbreaks, take one gram of lysine per a day. If you are experiencing the blisters characteristic of shingles, then take one gram of lysine three times daily.  We usually get our lysine from foods high in protein as our bodies are incapable of making lysine for themselves.

The chicken pox virus never goes away once you have had it, and fragments of the original virus are still contained in the body.  The fragments use an amino acid called arginine in order to grow but lysine blocks the arginine and therefore, blocks the growth of the shingles virus.

Lysine has been shown in clinical studies to block shingles from causing an outbreak and to heal existing blisters and also to shorten the road to healing once the blisters begin to fade.  Lysine is a master repairing agent in the body and so, taking lysine quickly causes the blisters and rashes caused by shingles to disappear.



The author of this story, Michelle Carraway, is a freelance contributor to National Nutraceuticals’ online news portals, which include Medicinal Mushroom Information Center, Amino Acid Information Center, Vancouver Health News and Today’s Word of Wisdom.  The opinions are the writer’s own and the owner and publisher of the site assume no responsibility for the accuracy of the content. Our articles are for informational, educational and entertainment purposes only. Please do your own due diligence, verify any health claims by doing additional research and consult your doctor before starting any supplementation program or making any lifestyle changes, including changes to your medication and supplementation.