Tag Archives: cognition

Antiaging Treatments – GABA Amino Acid, Lifestyle, or Ikaria?

Antiaging treatments have included creams and lotions, or even food and potions. People and even experts say things like… drink this, eat that, live here, go there, exercise more, eat less, eat healthier, live in the Andes mountains, take this supplement (like GABA amino acid), take that supplement (like Reishi medicinal mushrooms). 

Antiaging may even include a move to Ikaria (known as Icaria, a Greek island) like Stamatis Moraitis did, according to the New York Times article entitled: The Island Where People Forget to Die, discussing how he overcame cancer merely by choosing to move back home and altering his lifestyle. Stamatis Moraitis is a centenarian, meaning he is over one hundred years old, and still alive and well, sharp as a tack, and happy and healthy.

Anti-aging techniques and treatments for some people may or may not include GABA amino acid supplements, or a lot of small changes in lifestyle (or major ones, depending), but one thing is for sure… it is not usually just one thing, but a combination of many. Longevity can include heredity/genetics as well as environmental factors.

Longevity and aging gracefully may include supplements like GABA amino acid

Aging is associated with the body’s cells breaking down over time and not functioning at the levels that they used to when people were younger. Cells die and are not regenerated the same way. To overcome physical or biological entropy it is often recommended that not just living somewhere or eating a certain way is key (although both can promote health benefits, depending on the person), but sometimes changing all the “little things” in life so that they add up to become the “big things” all by themselves.

Little things can include dietary changes, exercise regimens, breathing techniques and yoga, distressing, skipping fast food and eating fresh fruit instead, and even taking GABA amino acid supplements.

What can GABA amino acid supplements do for you?

According to a demographic study by SV Ukraintseva, KG Arbeev, et al., on antiaging treatments, many of them legally prescribed for thirty years, more or less, some of the “most common of the relevant medicines are nootropic piracetam, gamma-aminobutyric acid (GABA), selegiline, Ginkgo biloba, pentoxifylline, cerebrolysin, solcoseryl, ergoloid, vinpocetin, sertraline, and estrogens, among others.” GABA amino acid is one of these popular items used for supplementation and antiaging.

GABA amino acid can have a variety of effects on your body, mind, and health. A general overview is covered in the article What Can GABA Amino Acid Do For Me?

GABA amino acid is also used to feel better, especially when one is in pain. Kill the Pain with Amino Acid GABA – Gamma-aminobutyric acid: Nature’s Pain Killer is an article on this very topic. Isn’t part of growing old feeling good and not being subject constantly to joints and inflammation, aches, and pains?

Additionally, protecting your brain and stimulating your senses and memory are key factors. Learning a language, or even knowing what GABA amino acid supplements can do to help your brain and memory or cognition can be read about here in Amino Acid GABA Vital For Normal Brain Activity And Memory. Memory is often a problem with dementia and Alzheimer’s as one gets older.

Although GABA amino acid is not the cure-all for all ailments, it is one of the many “little things” one can do to reduce pain, combat aging and restore a sense of youthfulness, health and wellness, and memory abilities. Perhaps it could still be included in many peoples’ little box of secret weapons against aging.




L-tyrosine And Vitamin D Links to Aging, Cognitive Decline

An animal study has led to greater understanding of the complex causes of cognitive decline in the aging brain. Cognitive decline is a factor in aging, but can this decline be prevented?  A study measured l-tyrosine nitration to investigate the role of Vitamin D in the aging brain.

The world population is aging. We can all expect to live longer, particularly if we live in developed countries. The percentage of people 80 and older is projected to increase fourfold over the next 50 years. And the proportion of people who live beyond the age of 100 is growing rapidly.

However, aging brains often suffer cognitive decline. Forgetfulness, inability to maintain focus, and a reduced capability to solve problems are common to all aging brains. Mild cognitive decline is an expected part of aging. But cognitive decline doesn’t affect all brains equally.

Cognitive decline can be caused by a variety of factors. Oxidative stress, which leads to free radicals damaging healthy cells, is one factor. Nitrosative stress is also a factor in cognitive decline. This occurs when nitrogen species act with reactive oxygen species to damage the healthy brain cells. But where does l-tyrosine fit into this picture?

A study from the Sanders Brown Center on Aging, University of Kentucky, examined the links between vitamin D deficiency and nitrosative stress. Can measuring l-tyrosine levels in the vitamin D-deficient brains help predict cognitive decline? Researchers J Keeney, S Forster, et al, developed an animal study to investigate.

Can measuring l-tyrosine combat cognitive decline?

Middle aged male rats were divided into three groups and fed either low vitamin D food, or high vitamin D food.  The diet continued for 5 months, then their brains were examined for evidence of oxidative and nitrosative stress.

One indication of nitrosative stress is the production of nitrol-tyrosine, which is caused by l-tyrosine nitration, which is a chemical process. L-tyrosine is an amino acid, produced in the body from phenylalanine. It is vital to general metabolism.

In this rat study, the low vitamin D group had much higher levels of nitrol-tyrosine. The study proved that vitamin D deficiency resulted in significant nitrosative stress in the brain, and that this nitrosative stress may cause cognitive decline.

The researchers concluded that proper nutrition, with adequate levels of vitamin D that help prevent l-tyrosine nitration, are necessary to prevent cognitive decline.