An animal study from Japan has found good news for ulcerative colitis sufferers. There is a possible new supplement, enriched with L-glutamine amino acid available on the market. This glutamine supplement could improve symptoms of colitis.

Ulcerative colitis is a chronic, long lasting disease. It’s an autoimmune disease, one of the forms of inflammatory bowel disease (IBD).  Crohn’s disease is the other form of IBD.

Ulcerative colitis is a very painful condition which results in inflammation and open sores inside the colon. The inflammation harms the lining of the colon, which leads to bleeding, production of pus, constant diarrhea, and pain.

There are currently no cures for ulcerative colitis, so the goal for existing medical therapy is to induce and maintain remission. The symptoms can go for months or even years. When not in remission, treatments focus on reducing the symptoms, and improving quality of life for the patients.

In serious cases, surgical removal of the colon and rectum may be suggested, though this obviously greatly impacts on quality of life. A glutamine supplement was studied, which may help in IBD cases.

Glutamine supplement study

E Joo, S Yamane, et al, researchers at the Laboratory of Sports and Exercise Medicine, Graduate School of Human and Environmental Studies, Kyoto University, Japan, investigated a new glutamine supplement for treating ulcerated colitis. The supplement contains the amino acid glutamine, fiber, and oligosaccharide.

A glutamine supplement has a variety of biochemical roles in the body, including improving gastrointestinal function. Glutamine supplement may help protect the lining of the gastrointestinal tract, which is damaged by ulcerative colitis.

The researchers tested mice, in which they induced colitis. The mice were given either the glutamine supplement, or a placebo, for ten days. The animals’ body weight loss and the measurable activity of colitis were tested.

Results of glutamine supplement for colitis

The glutamine supplement group had some impressive results. Their body weight loss and disease activity index were significantly lower. Additionally, intestinal inflammation was reduced with the glutamine supplement group.

The study concluded that a glutamine supplement has an excellent potential for a new therapy for ulcerative colitis.

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Sources:

http://www.ncbi.nlm.nih.gov/pubmed/23274091

There are currently no cures for ulcerative colitis, so the goal for existing medical therapy is to induce and maintain remission. The symptoms can go for months or even years. When not in remission,