Found in abundance in muscles and the brain, the dipeptide L-carnosine is an organic compound comprised of the amino acids histidine and beta-alanine. Because of the various ways L-carnosine can benefit cellular activity, such as slowing down the growth of cataracts and certain tumour cells, researchers at Aston University in Birmingham decided to study the mechanisms behind how L-carnosine works.

In doing so, they believe that it could lead to breakthroughs in L-carnosine helping treat and prevent age-related ailments such as Alzheimer’s, Parkinson’s, type 2 diabetes and cancer.

Study for L-carnosine for health benefits, numerous diseases, even anti-aging

Scientists Alan Hipkiss, Stephanie Cartwright, Clare Bromley, Stephane Gross and Roslyn Bill believe that L-carnosine slows down age-related biological disturbances through energy metabolism or proteostasis, which is a type of protein stabilization process. Since L-carnosine also acts as an antioxidant, it has the potential to be used as a drug that can target multiple diseases.

They report that L-carnosine can act as a compound to combine the heavy metal that causes cell damage in the system. In doing so, L-carnosine will effective prevent lipids, proteins and DNA from undergoing age-related damage (antiaging properties).

The researchers recall another recent study that supports the theory that L-carnosine can improve cognition in people living with schizophrenia.

For Alzheimer’s disease, L-carnosine can act as a neuroprotective agent and has been shown to inhibit problems in the mitochondria. The dipeptide can also eliminate mutated polypeptides and stimulate the production of stress proteins that will further work to rebalance the system.

Overall, the researchers are very hopeful that the antioxidant and anti-senescence qualities of L-carnosine can greatly help cell deterioration due to old age. They reviewed studies that show L-carnosine can help slow cells that cause cancer, Alzheimer’s disease, Parkinson’s disease and alleviate symptoms of diabetes.

More comprehensive studies will have to be completed but the outlook is promising that L-carnosine can be an effective form of treatment for a variety of health problems.

Source:

http://www.ncbi.nlm.nih.gov/pubmed/23442334