Category Archives: Leucine

Part 1: Eating Insects for Your Daily Amino Acids?

Pull up a chair and have a plate of bugs for breakfast?! Although this is not unrealistic or uncommon in most of the world, entomophagy (eating insects for food) brings a feeling of disgust for many in western societies, and a sourpuss face along with it! But eating insects is common to animals (insectivores), even other insects, as well as humans, and for good reasons.

Eating insects of many kinds brings to light the simple fact that they are full of protein and nutrition, and help sustain life. Vitamins, minerals, monounsaturated and polyunsaturated fats, oleic acid, and amino acids are only part of the full story.

In fact, bugs may wind up being a part of the human diet in the future, as it is currently in many countries, and has been prehistorically commonplace for hominids, hominins (human line), throughout time.

The big questions about eating insects include…

What amino acids are present in bugs and are they available to the human body? Exactly what nutritional content is covered for human requirements by consuming edible insects? Eating insects may be good for you, but do they taste good?

According to my daughter, who went to Peru with my mom and some friends and ate a large white grub that is a common to the area for consumption, it tasted lovely, just like an almond. She said, “It tasted good!” However, she also nearly gagged and spit it out. Why? The texture was “too mushy,” she said. The last thing she was thinking about was the amino acid content of the grub! *smiles*

Eating insects raw, such as her raw grub from Peru, are not always necessary. Most people around the world eat them raw as well as roasted, baked, smoked, fried, boiled in salted water, and dried or sun-dried. Of course, most Americans have heard of chocolate covered ants or grasshoppers as a delicacy dessert (or given as a joke, although is a serious meal in other countries). Each method of preparation makes eating insects a different experience, taste, texture, and can be the difference between it tasting good or wanting to spit it out on the ground from whence it came.

Who wants to eat bugs anyway? Lots of people, especially considering they are as easy to scavenge as they are to grow and raise for food, and is easier than gardening or raising small livestock. It is also cheaper than buying food at the grocery store, although bugs-on-a-stick (or loose) of many varieties can be purchased at local markets in many countries, like is often seen in China or Thailand.

The fact is that many grubs, larvae, grasshoppers, caterpillars, termites, palm weevils, mealworms, and other bugs are packed with nutrition such as potassium, calcium, sodium, magnesium, phosphorous, zinc, manganese, and copper according to the FAO. Eating insects can also supply you with necessary iron and amino acids like lysine, things that vegans and vegetarians are often deficient in.

CONTININUE READING Part 2: Eating Insects for Your Daily Amino Acids?

Reference:

http://link.springer.com/article/10.1007%2FBF00805837

http://www.organicvaluerecovery.com/studies/studies_nutrient_content_of_insects.htm

http://www.fao.org/docrep/018/i3253e/i3253e06.pdf

Egg Protein Powder for Your Essential Amino Acids – the Superior Choice?

Egg protein powder has been on the market for years and although not as popular as whey protein, it should be a consideration for those who wish to get a near perfect protein with all the essential amino acids. Why? The pattern in the egg whites, the egg protein nearly matches human growth.

Even without the egg yolk to supplement the body with cholesterol and fats, the protein of the egg provides some amazing nutrient potential. A top quality egg protein powder, can provide a good source of vitamins A, B, D and E.

Egg white protein digests at a moderate pace. It also possesses a high level of sulfur which is essential to various hormonal pathways within the body which in turn, leads to increased muscle mass.

Egg white protein doesn’t cause nearly the problems of bloating as whey protein, and contains all the essential amino acids, unlike hemp or soy.  Egg protein possesses a bland to slightly salty taste and also can easily be made into custom mixes in a shaker or blender.

Of course there is a negative to every protein powder. All this egg protein goodness doesn’t come cheap and consumers should be wary of buying low-grade egg protein powders.

Cheaper products from factory-farmed eggs should be avoided, for chickens in “chicken factories” often live in polluted environments that may even be toxic.  Chickens and their eggs can carry diseases such as salmonella and infections. In addition, factory-farmed eggs may include low levels of antibiotics, or hormones, or other pharmaceuticals.

Is egg protein powder the superior alternative for amino acids?

Both whey and egg protein powders have all the essential amino acids, and if a person doesn’t mind consuming a little cholesterol at a lower price, whey protein is probably the standard from which all other protein powders are judged from.

Another popular plant based protein powder could be hemp. It is low in a couple of essential amino acids, particularly lysine.  But, hemp is also generally considered a superfood. It is high also in essential fatty acids which may sound bad, but actually is really good because of the high amount of Omega 3 and Omega 6 fatty acids that many people are deficient in.

Soy protein powder also lacks two essential amino acids in sufficient quantities—methionine and lysine, which are particularly low. For overweight women, especially, soy powder may be great for soy is known for speeding up thyroid function which may be great for those who wish to shed a few pounds while reducing cholesterol. Soy protein powders also may be hugely beneficial for menopausal women, for the isoflavones can reduce hot flashes.

Having made all these comparisons in a nutshell, if you are looking for a zero-cholesterol, animal-based protein powder with all the essential amino acids, egg protein powder is tough to beat for many consumers today.

References:

http://superhumancoach.com/pros-and-cons-of-egg-protein-powder/

http://www.livestrong.com/article/481383-what-are-the-benefits-of-egg-white-protein-powder/

http://bestproteintoday.com/tag/amino-acids/

http://www.goodhempnutrition.com/content/68-what-is-hemp-protein

http://www.livestrong.com/article/467660-the-benefits-and-drawbacks-of-soy-protein-powder-in-women/

Amino Acids as Anti-Inflammatory Pain Relief

Did you know that amino acids can be used for pain relief? People often will take over the counter painkillers like acetomenaphen (e.g., Tylenol), or anti-inflammatories like ibuprofen (e.g., Advil), but a natural source of analgesics with some anti-inflammatory effects include amino acids. Amino acids are known as the building blocks of proteins, but they serve many functions in the body, especially to the organs and brain, or even the muscles and nerves. Taking amino acid supplements can sometimes aid the body to ward off pain and inflammation, just like a natural painkiller.

There are a couple of studies that tested amino acids like L-isoleucine, which can act as an agent for pain relief, and so prostaglandin was studied to see the effectiveness of L-isoleucine for the analgesic (painkilling) and anti-inflammatory properties. In order to understand how this works we must understand how prostaglandin works…

Prostaglandins are lipid compounds that work on-site like Aspirin; however, they are enzymatically derived (from fatty acids). Although prostaglandins work in a variety of ways, one of them is by acting as an analgesic, or natural pain reliever. Analgesics help your body achieve analgesia—relief from pain.

When there is an injury or you are will, the prostaglandins (whether due to amino acids or medicine) do not get secreted from the gland, but instead are chemically made on-site so they can be used exactly where they are needed, such as to control or reduce inflammation.

Amino acids studied as analgesics (pain relievers)

One study by E Ricciotti and GA FitzGerald regarding prostaglandins showed that they can act as a natural painkiller and help reduce the anti-inflammatory response. The researchers said, “prostaglandins may function in both the promotion and resolution of inflammation.” But amino acids may also cause a bodily anti-inflammatory response.

In a different study, four amino acids were investigated. The scientists RN Saxena, VK Pendse, and NK Khanna “Orally administered L-isoleucine, DL-isoleucine and L-leucine [which] exhibited anti-inflammatory activity in many test models of inflammation except formaldehyde-induced inflammation. L-beta-phenylalanine inhibited carrageenan-induced oedema only.”

Interestingly, it was the L-isoleucine that showed an extended analgesic (painkiller) result. Meanwhile, DL-isoleucine did have a short-lasting effect.

Unlike some supplements, the amino acids did not cause gastric ulceration nor did it promote acute toxicity in the doses that suppressed inflammation effectively. The researchers’ assessment on the painkilling amino acids included that the “anti-inflammatory activity seems to be related with interference with the action and/or synthesis of prostaglandins and deserves further intensive study.”

Of course, it depends on the problem and which amino acids you can use to act as a natural painkiller against it, so more research will continue in this area as time progresses.

References:

http://www.ncbi.nlm.nih.gov/pubmed/6335992

http://www.ncbi.nlm.nih.gov/pubmed/21508345

Amino Acids and Vitamins Improved Health in Elderly

As we age, it is generally believed our immune system deteriorates. It is considered a fact of life. Japanese researchers did a study to investigate the effects of supplementing amino acids and vitamins for both unhealthy and healthier older people for both inpatients and outpatients.

From the article, “Amino acid and vitamin supplementation improved health conditions in elderly participants”, Japanese researchers studied one bedridden inpatient group and one outpatient group.

Daily, a mixture of the amino acids containing leucine (1200 mg/day), glutamine (600 mg/day), and arginine (500 mg/day), plus 11 kinds of vitamins were administrated for 8 weeks. In both groups, general blood biomarkers such as C-reactive protein levels, white blood cell count, and natural killer (NK) cell activity were measured.

The study involved thirteen bedridden inpatients (7 males, 6 females; mean age, 81.8 ± 8 years) and eleven outpatients (7 males, 4 females; mean age, 74 ± 12 years) from the Sansei Hospital (Hyogo Prefecture, Japan).

These same amino acid and vitamins were administered to the inpatients as the outpatients with water twice daily, immediately after dinner and before sleeping.

Results from clinical study on Amino Acids and Vitamins

The researchers found that supplementation of the three amino acids arginine, glutamine, and leucine, and 11 kinds of vitamins had beneficial effects on the health of older people in poor health. The aging process in humans results in a condition called sarcopenia, which involves decreased skeletal muscle mass and function which is associated with metabolic diseases such as obesity and type 2 diabetes.

In this study, immune parameters were also evaluated. Of these, NK cell activity, an index of innate immunity, increased in both outpatients and inpatients. In the immune system, NK cell activity is thought to be one of the important indices for monitoring immunity because innate immunity is the first line of defense against infections. For those inpatients who were administered amino acids, their condition was stable due to increased NK cell activity.

To conclude, this study suggested that “dietary supplementation with the amino acids arginine (500 mg/day), glutamine (600 mg/day), leucine (1200 mg/day), and 11 kinds of vitamins for the elderly in poor health increased NK cell activity, irregardless of the presence of a primary disease and the amount of the daily nutrient intake.”

It was also observed that supplementation with more than 1 g/day of vitamin C enhanced immunity in healthy adults. In addition, vitamin E fostered the immunity for both unhealthy subjects (750 mg/day) and in healthy elderly subjects (800 mg/day).

References:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303480/

http://www.nia.nih.gov/health/publication/biology-aging/immune-system-can-your-immune-system-still-defend-you-you-age

Lower Blood Sugar – Essential Amino Acids and Diabetes

The question of whether essential amino acids and diabetes had a relationship was a question asked by researchers at the Biochemistry Research Department, part of the Vision Research Foundation in Chennai, India. What they wanted to look at was testing of free amino acids in type 2 diabetic patients to see if oral supplementation would affect these patients.

Diabetes is a disease where too much sugar (glucose) is in the blood. Some people can have type 1 diabetes from childhood, or get it later, but type 2 diabetes is more common, and is typically developed, chronic, and lifelong as well. Technically diabetes mellitus (DM) is a metabolic disease, where the body is unable to produce enough (or any) insulin, which causes these very high glucose levels in blood plasma of patients who have it.

In 2007, the amount of people diagnosed with diabetes, who were 20 years or older, equaled about 1.6 million. Today, in the United States alone, about 7.8 percent of the population—approx. 23.6 million people—have this serious and lifelong disease. The question of essential amino acids and diabetes comes into play because of glucose and insulin.

Insulin, the pancreas, and glucose

Insulin is a hormone created by the pancreas, which must be present in order for glucose to get into our cells (used by the body as food). However, with diabetes, the produces little to no insulin, so the cells do not respond properly, then glucose builds up in the blood and is excreted through the urine; therefore, even though the body has a large amount of glucose, all of that energy is lost. The hope, according to the scientists in India who wanted to test essential amino acids and diabetes, was that amino acids might help with blood glucose levels.

Essential amino acids and diabetes

In a pilot clinical trial the researchers, Sulochana K Natarajan, S Lakshmi, et al., had tested the glucose levels in the blood plasma of Streptozotocin-induced rats that were diabetic. Whether essential amino acids and diabetes, where the former would affect the latter, were related was the question, so they designed an oral test to determine if the effect of such amino acid supplements would help patients that had type 2 diabetes mellitus (DM).

77 subjects with type 2 diabetes participated for two months in a double blind pilot clinical trial. Both sexes, between the ages of 30-60, were involved in the trial and received oral antidiabetic tablets. The essential amino acids and diabetes link was examined by dividing the patients into two groups based on oral supplementation.

The supplements for essential amino acids and diabetes testing included:

1. Lysine

2. Essential amino acids

3. Amino acids and (fat-and-water-soluble) vitamins

4. Calcium phosphate (the control)

Regarding essential amino acids and diabetes, “essential” means that these aminos must be gotten from food or supplements since the body cannot produce them on its own.

Essential amino acids typically include:

Arginine
Carnitine
Histidine
Homocysteine
Isoleucine
Leucine
Lysine
Methionine
Phenylalanine
Taurine
Threonine
Trypthophan
Valine

The scientists tested the subjects who had essential amino acids and diabetes were examined for: fasting and post-prandial plasma glucose, plasma amino acids, glycosylated haemoglobin (HbA1c), fasting and post-prandial immunoreactive insulin, urea and creatinine in plasma and sugar, proteins and albumin, plus ketones and proteins.

The results of the trial “revealed a significant decrease in post-prandial plasma glucose (P<0.05) in group B when compared to groups C and D after 45 days. Plasma Arginine was increased in group C from 3.84 to 9.24 mg/dl.” Additionally, the patients having oral essential amino acids and diabetes (type 2) showed a “decrease … [in] plasma glucose without any change in plasma insulin levels, perhaps due to improved insulin sensitivity.”

Although this is good news regarding essential amino acids and diabetes, the long term effects of essential amino acids needs continued study.

References:

http://www.ncbi.nlm.nih.gov/pubmed/11887024

http://diabetes.niddk.nih.gov/dm/pubs/overview/

Connection between Folic Acid and Amino Acid Homocysteine

There is a connection between folic acid and amino acid homocysteine, but what is it? Folic acid and amino acid (homocysteine, one of the 22 amino acids) functions are quite different, but the former does affect the latter. In fact, blood levels of homocysteine in the body are lowered in the presence of folic acid.

Folic acid is also known as folate; however, folate is slightly different. Folate—a bioavailable and natural form of vitamin B9—comes from the word ‘foliage’ because it is found in leafy greens, such as spinach and other greens, but also from fortified/enriched cereals and animal foods like eggs or liver, as well as plant foods like broccoli, brussel sprouts, lentils, beans, asparagus, cantaloupe, and bananas. Folic acid is merely the synthetic form of folate, and is found in supplements.

Folic acid/folate (vitamin B9) helps the body produce energy, is needed for mental and emotional health, and helps prevent neural tube birth defects like spina bifida, which occurs during the first month of pregnancy, especially in high risk pregnancies. Folic acid deficiencies can occur in people due to alcoholism, celiac disease, and inflammatory bowel disease.

The terms (and products) folic acid and amino acid are two different things; where folic acid is vitamin B9, and amino acids like homocysteine, cysteine, leucine, lysine, carnitine, and so on, are simply the building blocks of proteins. All 22 common amino acids are found in protein foods such as meats (chicken, pork, beef, etc.) as well as fish and eggs. Eggs, then, are actually a good source of both folic acid and amino acid content.

So what is the connection between folic acid and amino acid homocysteine?

Although amino acids are necessary for health, sometimes it is not good to have too much of a good thing; homocysteine is one of these amino acids where elevated blood levels of the amino acid can actually cause health problems.

According to Dr. Weil, elevated homocysteine levels are “linked to an increased risk of heart attacks and strokes. Elevated homocysteine levels are thought to contribute to plaque formation by damaging arterial walls. High levels may also act on blood platelets and increase the risks of clot formation; however, whether high levels of homocysteine actually cause cardiovascular disease has yet to be agreed upon. … In addition, some evidence suggests that people with elevated homocysteine levels have twice the normal risk of developing Alzheimer’s disease.”

The folic acid and amino acid connection is affected by diet as well. People who eat a lot of meat in comparison to leafy greens (that have folate/folic acid) or fruits tend to be highest in homocysteine levels. B vitamins and folic acid help reduce homocysteine levels. Additionally, says Dr. Weil, “homocysteine is also produced in the body from another amino acid, methionine. One of methionine’s main functions is to provide methyl groups for cellular reactions. … Typically, homocysteine then receives another methyl group from either folic acid or vitamin B6 to regenerate methionine.”

Folic acid supplements usually come in .4 to .8 grams, but prescription strength is at 1 g/day, although older pregnant women or high risk moms can take up to 4+ g/day (doctor prescribed). If you are low in folic acid and amino acid levels supplements can be taken for either. High stress and increased coffee consumption can also raise homocysteine levels, however. Homocysteine levels can also be elevated due to psoriasis, kidney disease, or even low thyroid hormones.

Other than talking with your doctor, one of the best ways to deal with the folic acid and amino acid connection, especially if there is an issue, is to eat healthy, get enough exercise, and make sure your daily diet includes plenty of leafy greens and fresh fruits and vegetables and less meat and fried foods, which may also reduce cholesterol and aid cardiovascular health as an added bonus.

Sources:

http://umm.edu/health/medical/altmed/supplement/vitamin-b9-folic-acid

http://www.drweil.com/drw/u/ART03423/Elevated-Homocysteine.html

Help COPD with Amino Acids for Lung Disease

According to some researchers and there are a few amino acids for lung disease that exist and may help such issues. COPD (chronic obstructive pulmonary disease) is one of these lung conditions may be aided by amino acid supplements; in particular, those with even severe COPD. This lung disease affects the ability to breath and also reduces energy levels in those who have it. COPD may have different causes, but it can be a result of smoking cigarettes long term, as well as conditions such as emphysema. 

According to one study by RW Dal Negro, A Testa, et al., in Italy it was amino acids for lung disease that helped the patients with COPD. By supplementing COPD patients with certain essential amino acids they were able to determine if pulmonary rehabilitation might have improved health status and produce higher rates of physical performance.

Essential amino acids are several of the 22 commonly known amino acids. “Essential” means that they have to be gotten through diet since the body cannot produce them on its own. The list of essential amino acids may include: Valine, Threonine, Methionine, Leucine, Isoleucine, Phenylalanine, Tryptophan, Lysine, and Histidine.

Amino acids for lung disease – chronic COPD

A total of 88 COPD out-patients who had a 23 BMI (body mass index) or less were selected randomly to receive essential amino acids for lung disease (COPD) for a period of three months. After 12 weeks of the test period the patients receiving amino acids for lung disease had showed significant improvements in physical performance.

Also, the COPD patients scored higher on the SGRQ score (which measures breathing). Additionally, other areas were affected positively, as compared to the placebo group, who had taken the essential amino acids for lung disease (COPD), including improvements in: fat-free mass, serum albumin, increased muscle strength, oxygen saturation, and cognitive dysfunction.

The results produced greater confidence levels in the patients and the researchers for improvements in these symptoms that COPD usually negatively affects its patients. Essential amino acids may, then, help reduce symptoms of COPD, so it is clear that amino acids for lung disease can aid the patient in breathing easier as well as help their physical performance in a number of areas.

Source:

http://www.ncbi.nlm.nih.gov/pubmed/23193843

Essential Amino Acid Supplements and the Elderly

The world population is aging. More seniors are experiencing happy, active golden years, and many of us are caring for our elderly parents. Are there any amino acid supplements to help the elderly enjoy their lives to the fullest?

Birth rates are falling, and life expectancy is rising. In Canada today, there are as many people over the age of 65 as there are under the age of 16. This is great news for us all, as we can look forward to longer lives. But are there specific nutritional concerns we should be aware of?

Seniors are prone to muscle loss and muscle wastage, especially if they are ill or bedridden.  This muscle loss, or sarcopenia, can be debilitating, and if untreated can lead to dependence and a reduction in quality of life.

Muscle loss can be treated with a suitable exercise, healthy diet, and amino acid supplements or other supplements.

Essential amino acid supplements, are very useful for people who have lost their appetites and are not getting adequate nutrition. But can supplements treat muscle loss?

Muscles are built from protein, and protein is built from amino acids. We synthesize some of these amino acids in our bodies—the non-essential amino acids—but we must get many of them from the food we eat. These are known as essential amino acids, and these are often available as supplements.

Essential amino acid supplements – a good choice for muscle loss

Researchers (Elena Volpi, Hisamine Kobayashi, et al) published a report in The American Journal of Clinical Nutrition where they examined the amino acids responsible for stimulating muscle protein in elderly people. Healthy elderly subjects were chosen, and given essential amino acid supplements. The amino acids included:

  • histidine
  • isoleucine
  • leucine
  • lysine
  • methionine
  • phenylalanine
  • threonine
  • tryptophan
  • valine

Their muscle production was measured over time.

Results were positive. The essential amino acid supplements stimulated the production of muscle protein. The best results were from an essential amino acid supplement without carbohydrates.

Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192452/

All About Protein for Kids

What are proteins? If you are a kid or just want to learn all about protein in a simple way, then below is a simple explanation of what proteins are and why you need to eat them. Proteins help your body stay strong and builds muscle and other tissues (like organs and immune system) in your body. Some foods contain protein, such as beef, pork, fish, eggs, dairy products (like milk or cheese), nuts (like peanuts or peanut butter, almonds, walnuts) and seeds, as well as legumes (beans, lentils).

Your body knows all about protein because it uses specialized protein molecules to do certain tasks. For example, your body uses protein to make a part of your blood (red blood cells) that carries oxygen through your veins to all the other parts of your body; this part of the red blood cells is called hemoglobin. Another special part that protein is used for is to help keep the cardiac (heart) muscle strong. Proteins make your body parts–like legs and arms and organs–moving and keeps your immune system strong so you don’t catch diseases or get sick.

About protein and amino acids

If you eat protein, like a hamburger patty, then your digestive juices from your stomach and intestines start working to break the protein down into smaller parts called amino acids. Amino acids are the building blocks of protein. Then these amino acids can be used to make more proteins that help maintain your muscles, blood, bones, and organs.

At Kids Health they describe proteins as being like “long necklaces with differently shaped beads. Each bead is a small amino acid. These amino acids can join together to make thousands of different proteins.” There are over 200 different kinds of amino acids (“beads”) but only about 22 amino acids are common. About 13 of these amino acids are called non-essential amino acids because your body makes them automatically, but the other nine amino acids your body must get from food, so these are called essential amino acids (like arginine or leucine).

About protein types – complete and incomplete proteins

Complete proteins that have all nine essential amino acids come from animal sources, like meats and dairy. Vegetable sources of protein tend to be incomplete, however. If you want to know about protein sources that are both from vegetables and that are complete proteins you simply need to mix certain types of foods. Combining certain foods helps vegetarians (people who do not eat meat) get all their essential amino acids without eating animals or their products.

For example, some protein-rich vegetable-source foods that can be combined includes eating beans a rice, which are a staple food around the world for many developing countries. Another example is eating whole-grain bread and peanut butter together.

About proteins – how much do you need?

If you know how much you weigh then you can figure out just how much protein your body actually needs. Kids need about a half of a gram of protein for each pound (.5 kilograms) they weigh. That means they need a gram for every two pounds. If you weight 70 lbs then you need about 35 grams of protein each day. Adults usually need about 60 grams each day of protein.

Make sure you eat a balanced diet and if you want to see a chart about protein grams in food you can check this one out from the Moms Who Think website: http://www.momswhothink.com/diet-and-nutrition/high-protein-foods.html

References:

http://kidshealth.org/kid/nutrition/food/protein.html

http://www.momswhothink.com/diet-and-nutrition/high-protein-foods.html

Leucine Supplements Repair Heart Damage In Third Degree Burn Patients

An animal study investigated the effects of administering the amino acid leucine in reversing the heart damage caused by third degree (full thickness) burns.

Serious burns affect the heart as well as the skin. Burns range from superficial–first degree burns–to fourth degree burns. First degree burns heal very well over about ten days, but fourth degree can lead to amputation and death. Third degree burns, or full thickness burns, extend right through the skin. These burns can also lead to amputation.

These serious burns affect the cardiovascular system, too. Burns affect the heart’s ability to produce vital proteins, which it needs in order to pump effectively.

Most burns are caused by fire and hot liquids. These are known as thermal burns, and include scalding. Scalding is caused by hot liquids or gases. Thermal burns are common injuries, particularly in children.

Researchers (CH Lang, N Deshpande, et al) from the Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, USA, developed an animal study into burn-induced heart injury and the amino acid leucine.

The researchers knew that leucine stimulates the initiation of protein in skeletal muscles. They hoped the leucine would also stimulate protein in cardiac muscles.

Leucine is an essential amino acid, which means we must get it from our food. It’s particularly important in promoting muscle growth.

Would leucine reverse the heart damage caused by third degree burns?

In the animal study, anaesthetized rats were given a 40% total body surface third degree scald burn. Some were given leucine after 24 hours. The leucine group was compared to a control group, and there was also a non-burn control group.

The hearts of the burned rats suffered damage. The necessary protein was not synthesized in their hearts. However, the hearts of the burn rats given leucine showed a reversal of this cardiac damage.

The study concluded that leucine supplementation could repair the heart defects caused by serious burn injuries.

Sources:

http://www.ncbi.nlm.nih.gov/pubmed/15377887